The Cancer Genome Atlas identified four subtypes of endometrial cancer, and patients with DNA polymerase epsilon (POLE) ultramutated tumors have an improved prognosis. The high intermediate-risk subtype of endometrial cancer is a heterogenous group, and the patients with POLE in this group may benefit from surveillance instead of vaginal brachytherapy. This study sought to determine the cost-effectiveness of POLE testing in patients with stage I high intermediate-risk endometrial cancer.
Matthew Prest
He/Him
Physics PhD candidate at the City University of New York working on quantum information theory.